TITAN

TITAN is a tool for estimation of copy number variation (CNV) and loss of heterozygosity (LOH) in whole-genome sequencing data consisting of clonal cell populations. The TITAN algorithm uses hidden Marlov model (HMM).
Alternative name: TitanCNA

Topic

Genetics;Whole genome sequencing;DNA structural variation;Oncology

Detail

  • Operation: Polymorphism detection;Sequence analysis;Structural variation detection

  • Software interface: Command-line user interface;Library

  • Language: R

  • License: GNU GPL v3

  • Cost: Free

  • Version name: 1.22.0

  • Credit: British Columbia Cancer Foundation, the Canadian Institutes for Health Research (CIHR), Genome Canada/Genome British Columbia, Canadian Cancer Society Research Institute, the Terry Fox Research Institute, Michael Smith Foundation for Health Research, Natural Sciences and Engineering Research Council of Canada.

  • Input: -

  • Output: -

  • Contact: gavinha@gmail.com | gha@fredhutch.org | Sohrab P. Shah sshah@bccrc.ca

  • Collection: BioConductor

  • Maturity: Stable

Publications

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Download and documentation

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