MaxQuant
MaxQuant is a tool for the analysis of large mass-spectrometric data sets. The MaxQuant algorithm can manage large high-resolution data sets, uses many labeling procedures, and label-free quantification. MaxQuant has a viewer module to visualize 3-D graphical models. See also Perseus framework for statistical analysis of MaxQuant output.
Topic
Proteomics;Proteomics experiment;Statistics and probability
Detail
Operation: Imputation;Visualisation;Protein quantification;Statistical calculation;Standardisation and normalisation;Heat map generation;Clustering;Principal component plotting
Software interface: Graphical user interface
Language: -
License: -
Cost: Free
Version name: 1.6.17.0
Credit: The European Union’s Horizon 2020 Research and Innovation Programme
Input: Peptide identification CSV, TSV, SEQUEST .out file , xlsx
Output: CSV; JPG: PNG
Contact: cox@biochem.mpg.de | http://coxdocs.org/doku.php?id=maxquant:common:contact
Collection: -
Maturity: Mature
Publications
- Visualization of LC-MS/MS proteomics data in MaxQuant.
- Tyanova S, Temu T, Carlson A, Sinitcyn P, Mann M, et al. (2015). Visualization of LC-MS/MS proteomics data in MaxQuant. Proteomics 15(8): 1453-6.
- https://doi.org/10.1002/pmic.201400449
- PMID: 25644178
- PMC: PMC5024039
- Software lock mass by two-dimensional minimization of peptide mass errors.
- Cox J, Michalski A, Mann M (2011). Software lock mass by two-dimensional minimization of peptide mass errors. J Am Soc Mass Spectrom 22(8): 1373-80.
- https://doi.org/10.1007/s13361-011-0142-8
- PMID: 21953191
- PMC: PMC3231580
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification.
- Cox J, Mann M (2008). MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat Biotechnol 26(12): 1367-72.
- https://doi.org/10.1038/nbt.1511
- PMID: 19029910
- PMC: None
- The MaxQuant computational platform for mass spectrometry-based shotgun proteomics.
- Tyanova S, Temu T, Cox J (2016). The MaxQuant computational platform for mass spectrometry-based shotgun proteomics. Nat Protoc 11(12): 2301-2319.
- https://doi.org/10.1038/nprot.2016.136
- PMID: 27809316
- PMC: None
- Analysis of high accuracy, quantitative proteomics data in the MaxQB database.
- Schaab C, Geiger T, Stoehr G, Cox J, Mann M (2012). Analysis of high accuracy, quantitative proteomics data in the MaxQB database. Mol Cell Proteomics 11(3): M111.014068.
- https://doi.org/10.1074/mcp.M111.014068
- PMID: 22301388
- PMC: PMC3316731
- Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ.
- Cox J, Hein MY, Luber CA, Paron I, Nagaraj N, et al. (2014). Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ. Mol Cell Proteomics 13(9): 2513-26.
- https://doi.org/10.1074/mcp.M113.031591
- PMID: 24942700
- PMC: PMC4159666
Download and documentation
Source: http://coxdocs.org/doku.php?id=maxquant:common:download_and_installation
Documentation: http://coxdocs.org/doku.php?id=maxquant:start
Home page: http://www.maxquant.org/
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