ALRA
ALRA (Adaptively-thresholded Low Rank Approximation) is a tool for genotype imputation. The ALRA algorithm uses a low-rank approximation method to capture expressed gene dropouts. ALRA is also integrated into Seurat v3.0.
Topic
Population genetics;Transcriptomics;Gene expression
Detail
Operation: Imputation
Software interface: Command-line user interface;Library
Language: R
License: The MIT License
Cost: Free
Version name: -
Credit: The National Institutes of Health (NIH)
Input: scRNA-seq expression matrix
Output: -
Contact: Yuval Kluger yuval.kluger@yale.edu
Collection: -
Maturity: Emerging
Publications
- Zero-preserving imputation of scRNA-seq data using low-rank approximation
- Kaushik A, et al. miRMOD: a tool for identification and analysis of 5' and 3' miRNA modifications in Next Generation Sequencing small RNA data. miRMOD: a tool for identification and analysis of 5' and 3' miRNA modifications in Next Generation Sequencing small RNA data. 2015; 3:e1332. doi: 10.7717/peerj.1332
- https://doi.org/10.1101/397588
- PMID: -
- PMC: -
Download and documentation
Documentation: https://github.com/KlugerLab/ALRA/blob/master/README.md
Home page: https://github.com/KlugerLab/ALRA
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